The purpose of this study is to determine the maximum dose that is safely tolerated of the experimental drug Rhenium Re 188 P2045. This will be done by first treating patients at relatively low doses of Rhenium Re 188 P2045, observing them closely to assure that there are no bad side effects, then increasing the dose when we are confident that it is safe to do so.
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Maximum tolerated dose of Rhenium 188 P2045
Timeframe: Over the first month post dose administration
Safety of Technetium Tc 99m P2045 and Rhenium Re 188 P2045
Timeframe: Up to one year post study completion
Progression free survival in treated patients
Timeframe: Up to one year post study completion