Comparison of Two Bronchodilator Inhalers in Adolescents and Adults With Exercise-Induced Asthma

Inclusion Criteria: * Provide written informed consent * Male or non-pregnant, non-nursing females aged 12 40 years, inclusive, at the first screening visit * Have exercise-induced bronchospasm (EIB), with or without asthma, as demonstrated by a ≥15% decrease in pre-challenge absolute FEV1 observed up to 60 minutes following an exercise challenge conducted at the first screening visit * Predicted FEV1 ≥70% for age, height, gender, and, where applicable, race following an 8 hour period without \[beta\]2 agonist use * Have no contraindications for exercising maximally * Ability to perform spirometry reproducibly (i.e., the difference between the two highest FEV1 values out of a minimum of three and a maximum of eight values obtained at the first screening visit must not exceed 0.2 L) * Ability to self-perform PEF (peak expiratory flow) determinations with a handheld peak flow meter * Can tolerate withdrawal of applicable medications for qualification at both screening visits * Normal chest X ray, or, if abnormal, is consistent with asthma and shows no evidence of other active disease * Otherwise healthy individuals with clinically acceptable medical history, physical examination, vital signs, and 12 lead ECG (electrocardiogram; with 30 second Lead II rhythm strip) * Body mass index (BMI) of 19 29 kg/m2 (BMI = weight \[kg\] / height2 \[m\]) * Non-smokers for at least one year prior to the first screening visit and have maximum smoking histories of ten-pack years (i.e., equivale…