Endoscopic Placement of Metal Stents in Treating Patients With Cancer- Related Duodenal Obstruction (NCT00004910) | Clinical Trial Compass
CompletedPhase 1/2
Endoscopic Placement of Metal Stents in Treating Patients With Cancer- Related Duodenal Obstruction
United StatesStarted 2000-01
Plain-language summary
RATIONALE: The use of endoscopy to place metal stents in the duodenum is less invasive than surgery for treating cancer-related duodenal obstruction and may have fewer side effects and improve recovery.
PURPOSE: Phase I/II trial to study the effectiveness of endoscopic placement of metal stents in treating patients who have cancer-related obstruction of the duodenum.
Who can participate
Age range18 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
DISEASE CHARACTERISTICS:
* Endoscopically confirmed localized tumor as the cause of duodenal obstruction
* All primary tumor types are eligible
* No prior duodenal Wallstents
* Must have symptoms of gastrointestinal obstruction, including:
* Inability to move bowels, absence of flatus, nausea/vomiting, abdominal pain, or diarrhea
PATIENT CHARACTERISTICS:
Age:
* 18 and over
Performance status:
* ECOG 0-3
Life expectancy:
* Not specified
Hematopoietic:
* Platelet count greater than 50,000/mm\^3
Hepatic:
* INR no greater than 1.5 times upper limit of normal
Renal:
* Not specified
Cardiovascular:
* No cardiac condition
Other:
* Not pregnant or nursing
* Fertile patients must use effective contraception
* No significant active infection (e.g., pneumonia, peritonitis, or wound abscess) that would preclude endoscopy
* No other serious concurrent illness
* No uncontrolled metabolic disease (e.g., diabetes mellitus or hypothyroidism)
* No dementia, psychiatric disorder, or altered mental status that would preclude compliance
* History of other neoplastic disease allowed
* Veterans Administration patients are not eligible
PRIOR CONCURRENT THERAPY:
Biologic therapy:
* Not specified
Chemotherapy:
* Prior or concurrent chemotherapy allowed
Endocrine therapy:
* Not specified
Radiotherapy:
* Prior or concurrent radiotherapy allowed
Surgery:
* At least 3 weeks since prior surgery and recovered