High-dose ICE With Amifostine

Eligibility Criteria: * Histologically documented malignancy * Metastatic or locally unresectable malignancy * Patient may be responding to therapy * Responding Stage IIIC/IV or recurrent/refractory ovarian carcinoma (ineligible for other bone marrow or stem cell transplant protocols) * Relapsed germ cell carcinomas * Relapsed lymphomas (ineligible for other BMT or SCT protocols * SCLC in PR or CR * Sarcomas in or near complete remission after induction chemotherapy * Stage IIIB NSCLC responding to chemotherapy * Responsive bladder, head and neck carcinoma, or carcinoma of unknown primary * Other tumors without curative or first line therapy (not eligible for phase II or III studies) * Aged 18 to 55 Physiologic years \-- Performance status: PS 0-1 * Prior Treatment * \> 1 week since surgery or RT * \> 3 weeks since prior CT * Informed Consent * Required initial laboratory data: * White Cell Count Life ≥ 3000/ul * Platelet Count ≥ 100,000/ul * Creatinine ≤ 1.5 x normal * Bilirubin ≤ 1.5 x normal * No current metastases * BM Asp \& Bx * Brain CAT * Creatinine Clearance ≥ 60 cc/min * SGOT \< 2.5 x normal * No other serious medical or psychiatric illness which would prevent informed consent or general anesthesia * Uncontrolled or severe cardiovascular disease including recent (\< 6 months) myocardial infarction, or congestive heart failure * Active uncontrolled bacterial, viral, or fungal infection; or an active duodenal ulce…