Evaluation of Patients With Liver Disease (NCT00001971) | Clinical Trial Compass
RecruitingNot Applicable
Evaluation of Patients With Liver Disease
United States8,050 participantsStarted 1992-05-27
Plain-language summary
The proposed study aims to evaluate, investigate, and follow-up patients suffering from acute and chronic liver disease. The study will focus on understanding diseases affecting the liver.
Patients participating in the study will first undergo a routine check-up as an outpatient. They will be asked to provide blood and urine samples for laboratory testing and will undergo an ultrasound of the liver. Ultrasound examinations use sound waves to determine the size and texture of the liver. After the initial visit subjects will be requested to follow-up once a year at the outpatient department for a similar check-up.
Additional tests may be requested throughout the study to provide information for other research studies and individual consent will be requested. These tests may include liver biopsies, skin biopsies, and / or specialized blood, plasma, and lymphocyte examinations.
Subjects that qualify for medications presently being studied may be offered the opportunity to benefit from experimental therapy.
Who can participate
Age range2 Years – 100 Years
SexALL
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Inclusion criteria
✓. \>=2 years of age.
✓. Meets one of the following:
✓. Suspected or evidence of acute or chronic liver disease on evaluation by a referring licensed independent practitioner (LIP), OR
✓. At risk for acute or chronic liver disease
✓. \>= 18 years of age.
✓. In good general health as evidenced by medical history
Exclusion criteria
✕. Any chronic medical condition, including (but not limited to) heart, kidney, or lung diseases
✕. Taking any regular medications or supplements (with the exception of regular multivitamins and/or oral contraceptives)
✕. Average alcohol consumption \> 1 drink/day in past 6 months, per self-report
✕. History of liver disease (with the exception of neonatal jaundice)
What they're measuring
1
Predisposition and outcomes related to liver disease susceptibility, progression, and treatment response
Timeframe: Annual visits
Trial details
NCT IDNCT00001971
SponsorNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)