Serious Bacterial Infection

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Serious Bacterial Infection trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 5 trials

RecruitingPhase 2

NCT05639647

Study of 2 Medicines (Aztreonam and Avibactam) Compared to Best Available Therapy for Serious Gram-negative Infections

The purpose of this study is to evaluate how Aztreonam (ATM) and Avibactam (AVI) are processed in pediatric participants. This study also aims to understand par…

United States, China48 participantsStarted 2023-04-18

Treatment: ATM-AVI, BAT

RecruitingNot Applicable

NCT07134751

Febrile Infants Swedish Study

Approximately one million febrile infants aged ≤60 days present annually to pediatric emergency departments (PEDs) in Europe and the United States. Although few…

Sweden2,000 participantsStarted 2025-12-01

RecruitingPhase 3

NCT06954441

V-IMMUNE: A Novel Immunoglobulin Therapy for Immunodeficiency

This is a phase III, non-randomized clinical trial (VIP Study) designed to assess the safety and efficacy of V-IMMUNE®, a 5% human normal immunoglobulin prepara…

Brazil50 participantsStarted 2025-08-15

Treatment: Intravenous immunoglobulin (IVIG)

RecruitingNot Applicable

NCT06824350

Clean Trial - Chlorination to Reduce Enteric and Antibiotic Resistant Infections in Neonates

The CLEAN (ChLorine to reduce Enteric and Antibiotic resistant infections in Neonates) cluster randomized controlled trial in western Kenya will evaluate the im…

United States, Kenya45,450 participantsStarted 2025-01-21

Treatment: chlorination for water disinfection and surface disinfection, infection prevention and control messaging

RecruitingNot Applicable

NCT05817825

Pilot Testing a Novel Remotely Delivered Intensive Outpatient Program for Individuals With OUD

This study aims to test a remotely delivered IOP program ("SmartIOP") for OUD patients who are hospitalized for serious injection-related infections. This will…

United States20 participantsStarted 2023-11-17

Treatment: Smart IOP Intervention, Peer Recovery Coach

All recent trials (46 shown)

Not Yet RecruitingPhase 2

NCT07550595

Oritavancin for Treatment of Serious Cardiac Infections

Cardiac infections, including infective endocarditis and cardiovascular implantable electronic device infections, are associated with substantial morbidity and…

Australia20 participantsStarted 2026-07-01

Treatment: Oritavancin, Oritavancin

CompletedNot Applicable

NCT02060513

Study of Accuracy of New Diagnostic Technology to Determine Guide Rapid Antibiotic Treatment for Serious Infections

Military service members and the U.S. veteran population face a growing and serious health threat: widespread antibiotic resistance resulting from resistant bac…

United States2,298 participantsStarted 2013-08

Serious Bacterial Infection

Trial phase breakdown

Trial status

Actively recruiting — 5 trials

Study of 2 Medicines (Aztreonam and Avibactam) Compared to Best Available Therapy for Serious Gram-negative Infections

Febrile Infants Swedish Study

V-IMMUNE: A Novel Immunoglobulin Therapy for Immunodeficiency

Clean Trial - Chlorination to Reduce Enteric and Antibiotic Resistant Infections in Neonates

Pilot Testing a Novel Remotely Delivered Intensive Outpatient Program for Individuals With OUD

All recent trials (46 shown)

Oritavancin for Treatment of Serious Cardiac Infections

Study of Accuracy of New Diagnostic Technology to Determine Guide Rapid Antibiotic Treatment for Serious Infections

Trial phase breakdown

Trial status

Actively recruiting — 5 trials

Study of 2 Medicines (Aztreonam and Avibactam) Compared to Best Available Therapy for Serious Gram-negative Infections

Febrile Infants Swedish Study

V-IMMUNE: A Novel Immunoglobulin Therapy for Immunodeficiency

Clean Trial - Chlorination to Reduce Enteric and Antibiotic Resistant Infections in Neonates

Pilot Testing a Novel Remotely Delivered Intensive Outpatient Program for Individuals With OUD

All recent trials (46 shown)

Oritavancin for Treatment of Serious Cardiac Infections

Study of Accuracy of New Diagnostic Technology to Determine Guide Rapid Antibiotic Treatment for Serious Infections

Dose-finding, Pharmacokinetics, and Safety of VABOMERE in Pediatric Subjects With Bacterial Infections

Expanded Access to Fosmanogepix for Patients With Serious or Life-threatening Invasive Fungal Infections

Efficacy, Safety, and Tolerability of ATM-AVI in the Treatment of Serious Infection Due to MBL-producing Gram-negative B…

Immunisation for Adolescents Against Serious Communicable Diseases (B Part of it NT)

A Study to Compare Different Drugs Used to Prevent Serious Bacterial Infections in HIV-Positive Children

A Study of Three Drugs Plus Zidovudine in the Prevention of Infections in HIV-Infected Patients

Randomized Comparative Study of Fluconazole Versus Clotrimazole Troches in the Prevention of Serious Fungal Infection in…

An Open, Prospective, Multicenter Study of Trimetrexate With Leucovorin Rescue for AIDS Patients With Pneumocystis Carin…

TD-1607 SAD Study in Healthy Subjects

Randomized-controlled Trial (RCT) on Combination Antibiotic for Infections Caused by Gram-negative Bacteria

Efficacy, Safety, Tolerability of Vabomere Compared to Best Available Therapy in Treating Serious Infections in Adults

Efficacy and Safety Study of Brilacidin to Treat Serious Skin Infections

Study of Cases of Serious Infections Due to Carbapenem-Resistant Enterobacteriaceae

New Protocol for Febrile Neonate Management

Effectiveness of Rifabutin in the Treatment of Mycobacterium Avium Complex

Study of Accuracy of New Diagnostic Technology to Guide Rapid Antibiotic Treatment for Serious Infections

Fever and Shivering: Frequency and Role in Predicting Serious Bacterial Infection

A Study Of The Safety, Tolerability And Effective Of Voriconazole For The Treatment Of Serious Candida Infection And Can…